The DeriveLift extension has landed in GHC HEAD, so now it's become apparent that the bikeshed needs a new coat of paint. The only Lift instances at the moment are base types [1], but with DeriveLift, it would be possible to implement Lift for many for data types with ease.
I'll make (what I hope is) an uncontroversial first suggestion: we should derive Lift for every data type in the template-haskell library itself. These instances have proved to be useful for library authors who need to convert to and from the TH AST (th-desugar, for example, relies on this functionality via orphan instances [2]).
Adding this would break some code out in the wild (the th-lift [3] and th-orphans [4] packages come to mind; there may be others), so I'll request feedback before marching forth with this proposal.